The Avian Chb6 Alloantigen Triggers Apoptosis in a Mammalian Cell Line

Apoptosis in a Mammalian Cell Line The Avian Chb6 Alloantigen Triggers

P.oleracea induced apoptosis and inhibited the cell growth in oral epithelial cancer cell line

Despite the progress in cancer therapies such as chemotherapy and radiation, its eradication remains as unattainable dream for the patients and doctors. Recently, using supplementary agents such as herbal medicine with fewer side effects seems efficient and attractive. Therefore, the purpose of the present study is to investigate if the ethanolic extract of P.oleracea has cytotoxicity and apopt...

Binding of lactoferrin to IGBP1 triggers apoptosis in a lung adenocarcinoma cell line.

BACKGROUND Lactoferrin (Lf), an iron-binding protein present in mammalian secretions, plays important roles in cancer prevention by inducing apoptosis. MATERIALS AND METHODS PC-14 lung adenocarcinoma cells were exposed to bovine Lf (bLf) protein and the expression of caspase-3 and apoptosis protease-activating factor-1 (APAF-1) was assessed. To investigate the molecular mechanism of apoptosis...

Triggers of hair cell regeneration in the avian inner ear.

We performed an in vitro study in order to determine possible triggers of hair cell regeneration in the chick basilar papilla following degeneration. We compared the response of sensory epithelium damaged by collagenase treatment with that damaged by acoustic trauma. The former exhibited no proliferative activity, but the latter did. The basilar papillae damaged by acoustic trauma could have pr...

Enhanced calreticulin expression triggers apoptosis in the MCF-7 cell line.

Calreticulin, since its discovery as a ubiquitous protein of endoplasmic reticulum, has become recognized as a multifunctional luminal resident protein affecting many cellular functions ranging from development to death of a cell. However its role in cancer and significance for therapy remains to be clarified. Here to examine its effects, the calreticulin gene was over expressed in MCF-7 human ...